Información de la droga para PRAMIPEXOLE DIHYDROCHLORIDE 0.125 mg, 0.25 mg, 0.5 mg, 1 mg, and 1.5 mg Tablets (Barr Laboratories Inc.): DESCRIPTION

  • Pramipexole dihydrochloride tablets contain pramipexole, a nonergot dopamine agonist. The chemical name of pramipexole dihydrochloride is (S)-2-amino-4,5,6,7-tetrahydro-6-(propylamino) benzothiazole dihydrochloride monohydrate.

    The structural formula is:

    Pramipexole dihydrochloride is a white to off-white powder substance. Melting occurs in the range of 296°C to 301°C, with decomposition. Pramipexole dihydrochloride is more than 20% soluble in water, about 8% in methanol, about 0.5% in ethanol, and practically insoluble in dichloromethane.

    Pramipexole dihydrochloride tablets, for oral administration, contain 0.125 mg, 0.25 mg, 0.5 mg, 1 mg, or 1.5 mg of pramipexole dihydrochloride monohydrate. Inactive ingredients consist of corn starch, hydrogenated vegetable oil, mannitol, povidone and pregelatinized corn starch.

  • Drug Information Provided by National Library of Medicine (NLM).